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阻塞性睡眠呼吸暂停患者的DISE指导的手术失败:系统性审查和元分析

Yingting Qi^1,2, Yi Zhao^1,2, Yan Yan³

¹Department of Otolaryngology Head and Neck Surgery, Peking University Third Hospital, No. 49 Huayuan North Road, Haidian District, Beijing, 100191, People's Republic of China.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

|February 7, 2024

概括

药物诱导睡眠内镜 (DISE) 引导的阻塞性睡眠呼吸暂停 (OSA) 上呼吸道手术失败率为37%. DISE识别了关键的阻塞部位,有助于手术规划和改善OSA患者的治疗结果.

科学领域:

耳鼻喉科耳鼻喉科耳鼻喉科
睡眠医学睡眠医学
手术结果研究研究.

背景情况:

阻塞性睡眠呼吸暂停 (OSA) 是一种常见的疾病,通常用上呼吸道手术治疗.
DISE指导的OSA手术的有效性和失败因素尚未得到充分证实.
确定特定的阻塞部位对于手术成功至关重要.

研究的目的:

在OSA患者中,通过药物诱导睡眠内镜 (DISE) 引导的上呼吸道手术的失败率.
识别导致手术失败的特定上呼吸道阻塞部位.
分析与OSA手术失败相关的风险因素.

主要方法:

一个系统的审查和对发表到2023年5月之前的研究进行元分析.
搜索的数据库包括PubMed,Embase,科学网和谷歌学者.
纳入标准:使用DISE进行手术前评估的研究,报告OSA患者的失败率和结果.

主要成果:

分析了25项涉及1522名患者的研究.
在DISE引导的上呼吸道手术中,整体失败率为37%.
失败的危险因素包括皮膜崩,口侧壁崩,舌头底部崩,高BMI和高的呼吸暂停-呼吸暂停指数.

结论:

由DISE指导的上呼吸道手术在OSA治疗中表现出37%的失败率.
DISE有效地识别了关键阻塞部位,指导单一和多层次的外科干预.
了解这些阻塞模式和风险因素可以优化OSA的手术策略.

关键词:

药物诱导睡眠内镜药物诱导睡眠内镜阻塞性睡眠呼吸暂停症是什么风险因素风险因素手术失败导致的手术失败.

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