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Updated: Jul 4, 2025

Author Spotlight: Achieving High-Purity In Vitro Differentiation of Th17 Cells Using Cytokine Concentration Modulation
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Published on: October 25, 2024

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TCR信号诱导STAT3酸化以促进TH17细胞分化

Zhen Qin1, Ruining Wang1, Ping Hou1

  • 1Department of Immunology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.

The Journal of experimental medicine
|February 7, 2024
PubMed
概括

T细胞分化依赖于细胞因子信号,但TCR刺激也会激活STAT3. 这一意想不到的发现揭示了TCR信号如何控制TH17和Treg细胞平衡,为自身免疫性疾病提供了新的治疗点.

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