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Updated: Jul 4, 2025

Strategic Screening and Characterization of the Visual GPCR-mini-G Protein Signaling Complex for Successful Crystallization
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Strategic Screening and Characterization of the Visual GPCR-mini-G Protein Signaling Complex for Successful Crystallization

Published on: March 16, 2020

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扩大G蛋白合受体Rhodopsin的功能分析

Benjamin M Scott1, Steven K Chen1, Alexander Van Nynatten1

  • 1Department of Cell and Systems Biology, University of Toronto, Toronto, ON, Canada.

Journal of molecular evolution
|February 7, 2024
PubMed
概括

我们开发了一种高通量试验,用于测量G蛋白结合受体 (GPCR) 罗多普辛的突变. 这种深度突变扫描方法揭示了突变如何影响罗多素激活和蛋白质结构,有助于了解疾病变异.

关键词:
G蛋白结合受体的受体是G蛋白结合受体的受体.高通量酵母试验法 酵母试验法罗多普辛的结构和功能

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A Rhodopsin Transport Assay by High-Content Imaging Analysis12:11

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