从与咖啡粉混合的一次性可生物降解饮用吸管中释放的挥发性成分的潜在安全问题:化学空间视角
Hanke Li1, Qi-Zhi Su1, Jinxin Liang2
1National Reference Laboratory for Food Contact Material (Guangdong), Guangzhou Customs Technology Center, Guangzhou 510075, China; State Key Laboratory of Pulp and Paper Engineering, South China University of Technology, Guangzhou 510641, China.
Journal of hazardous materials
|February 7, 2024
概括
经过磨碎的咖啡吸管 (CGS) 显示了增强的生物降解性,但存在安全风险. 分析显示,与其他类型的草相比,CGS中挥发性有机化合物 (VOC) 的遗传毒性和估计每日摄入量 (EDI) 更高.
科学领域:
- 食品科学 食品科学 食品科学
- 环境科学 环境科学
- 毒理学 毒理学 毒理学
背景情况:
- 由消耗的咖啡粉 (CGS) 制成的一次性饮用吸管提供了增强的生物降解性.
- 然而,它们复杂的化学成分引发了关于挥发性有机化合物 (VOC) 的潜在安全问题.
研究的目的:
- 描述和评估与聚乳酸吸管 (PLAS) 和聚烯吸管 (PPS) 相比,咖啡粉吸管 (CGS) 中的VOC的安全性.
- 评估已识别的VOC的潜在遗传毒性和估计每日摄入量 (EDI).
主要方法:
- 用头部空间固体相微提取和迁移试验来识别VOCs.
- 气色谱质谱法 (GC-MS) 在CGS中确定了430个VOC,在PLAS/PPS中确定了153个VOC.
- 定量结构-活性关系 (QSAR) 分析和EDI计算评估了毒性.
主要成果:
- CGS含有更多的VOC和多样性,其中许多引发了遗传毒性警报.
- 在CGS中37.9%的VOC的EDI超过了0.15μg/人/天的安全门.
- 由于存在重大危害和在CGS中更高的检测率,14种VOC被优先考虑.
结论:
- 在CGS中的VOC比PLAS和PPS中的VOC具有更大的遗传毒性和摄入风险.
- 化学空间分析表明,高风险的挥发性有机化合物与电子阴性和醇/水分区系数相关.
- 调查结果为改善可持续食品接触材料中CGS化学安全和消费者健康提供了关键数据.
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