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相关概念视频

MicroRNAs01:22

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MicroRNA (miRNA) are short, regulatory RNA transcribed from introns—non-coding regions of a gene—or intergenic regions—stretches of DNA present between genes. Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After...
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RNA interference (RNAi) is a cellular mechanism that inhibits gene expression by suppressing its transcription or activating the RNA degradation process. The mechanism was discovered by Andrew Fire and Craig Mello in 1998 in plants. Today, it is observed in almost all eukaryotes, including protozoa, flies, nematodes, insects, parasites, and mammals. This precise cellular mechanism of gene silencing has been developed into a technique that provides an efficient way to identify and determine the...
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Small interfering RNAs, or siRNAs, are short regulatory RNA molecules that can silence genes post-transcriptionally, as well as the transcriptional level in some cases. siRNAs are important for protecting cells against viral infections and silencing transposable genetic elements.
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Lung microRNA Profiling Across the Estrous Cycle in Ozone-exposed Mice
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运动和微型眼镜

M Pala1

  • 1Malatya Turgut Ozal University, Faculty of Medicine, Department of Physiology, Turkey.

Georgian medical news
|February 7, 2024
PubMed
概括
此摘要是机器生成的。

身体活动通过分子途径诱导有益的适应,包括微RNAs (miRNAs). 这些小RNA分子调节基因表达,并可作为运动适应和伤害预防的生物标志物.

科学领域:

  • 运动生理学和分子生物学
  • 遗传学和表观遗传学
  • 生物化学和生物信息学

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背景情况:

  • 身体活动推动了对终身健康的关键适应.
  • 运动效益的分子机制仍在被发现.
  • 微RNAs (miRNAs) 是基因表达的关键调节者.

结论:

  • 改变的miRNA档案反映了适应体力活动的情况.
  • miRNAs显示出监测运动状态和预防受伤的潜力.
  • 对miRNA功能的进一步研究可以优化运动干预措施.