使用超声波剪切波弹性学进行丸扭曲的非侵入性评估:一项实验性研究
Yunyong Lin1, Wenjie Lu1, Guojing Li2
1Department of Ultrasound, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Ultrasonography (Seoul, Korea)
|February 7, 2024
概括
用剪波弹性图 (SWE) 测量的丸硬与丸扭曲后的精子发生障碍有显著的相关性. SWE可以非侵入性地评估丸损伤的程度,并预测精子发生的结果.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 生殖医学 生殖医学
- 医疗成像医学成像
背景情况:
- 丸扭曲是一种需要及时诊断和治疗的外科紧急情况.
- 评估丸损伤的程度和预测扭曲后的生育结果仍然具有挑战性.
- 非侵入性成像模式对于评估丸活力和功能至关重要.
研究的目的:
- 在诱导丸扭曲后在不同时间点使用剪波弹性图 (SWE) 调查丸刚度的变化.
- 评估丸硬性对扭曲后的精子生成的预测能力.
- 为了确定标志性SWE发现,表明丸扭曲和相关损伤.
主要方法:
- 60只子经历了完全或不完全的丸扭曲,或作为对照.
- 用SWE进行部超声波,在术前和术后,按设定的时间间隔进行.
- 用反复测量分析差异和接收器操作特征 (ROC) 曲线来分析SWE数据并评估诊断性能.
主要成果:
- 在中部和外围丸区域的SWE值和精子生成 (分别r=-0.759和r=-0.696) 之间观察到显著的负相关性.
- 在低精子发生和精子发生停止之间区分方面,SWE表现出高的诊断性能 (AUC 0.886和0.824).
- "硬环标志"被确定为SWE在丸扭转中的特征性发现.
结论:
- 用SWE测量的丸硬度与扭曲的持续时间和严重程度相关.
- SWE是一种有前途的非侵入性工具,用于评估扭转丸的精子发生损伤.
- "硬环标志"是SWE成像中丸扭曲的一个关键指标.
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