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Updated: Jul 4, 2025

Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules
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具有脊柱中心神经网络能量功能的含腔蛋白质的新设计

Yang Xu1, Xiuhong Hu1, Chenchen Wang2

  • 1Department of Rheumatology and Immunology, The First Affiliated Hospital of USTC, Centre for Advanced Interdisciplinary Science and Biomedicine of IHM, Hefei National Center for Interdisciplinary Sciences at the Microscale, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui 230001, China; MOE Key Laboratory for Membraneless Organelles and Cellular Dynamics, Hefei National Laboratory for Physical Sciences at the Microscale, School of Life Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui 230027, China.

Structure (London, England : 1993)
|February 7, 2024
PubMed
概括

研究人员使用数据驱动的方法设计了具有小分子结合腔的新型蛋白质骨干. 实验验证证了这些新型蛋白质对目标功能的潜力.

关键词:
蛋白质设计 蛋白质设计结构生物学结构生物学

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