COVID-19 疫情是否对口腔癌的分期有影响? 一个单一中心的回顾性观察性研究
Joshua Lopez1, Shadaab Mumtaz2, Ali Amini2
1Department of Oral and Maxillofacial Surgery, Royal Free London NHS Foundation Trust, Wellhouse Lane, Barnet, Hertfordshire, EN5 3DJ, UK. joshua.t.j.lopez@gmail.com.
British dental journal
|February 7, 2024
概括
随着COVID-19的流行,口腔癌的阶段可能变得更糟,在疫情期间观察到的高级诊断率更高. 需要进一步的长期研究来证实这些发现对口腔癌患者.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 全球范围内,COVID-19大流行严重扰乱了医疗保健系统.
- 早期癌症诊断和分期对于有效的口腔癌治疗结果至关重要.
- 疫情对包括口腔癌在内的癌症护理途径的影响需要进行调查.
研究的目的:
- 为了评估COVID-19流行病对英国一家教学医院口腔癌阶段化的影响.
- 为了比较口腔癌的诊断和疫情前和疫情高峰期间之间的分期.
主要方法:
- 从伦敦一家教学医院的头癌症数据库中对口腔癌病例的回顾性分析.
- 将2019-2020年3月 (大流行前) 与2020-2021年3月 (大流行高峰) 的数据进行比较.
- 对口腔癌患者的转诊来源和TNM分期的评估.
主要成果:
- 在这两个时期,诊断出类似数量的口腔癌病例 (25例在流行前,26例在流行期间).
- 在大流行期间,牙医推率下降 (48%至30%) 被观察到.
- 在大流行期间 (48%至68%) 观察到更高的晚期口腔癌 (TNM 4a及以上) 发病率.
结论:
- 该研究观察到,在COVID-19流行病的第一年,口腔癌的阶段化趋势更为先进,尽管差异在统计学上并不显著.
- 减少牙医的转诊可能导致诊断延迟.
- 建议进行长期的多中心研究,以充分确定大流行对口腔癌患者结果的影响.
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