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Updated: Jul 4, 2025

Standardized Rat Coronary Ring Preparation and Real-Time Recording of Dynamic Tension Changes Along Vessel Diameter
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多克索鲁比改变了大鼠冠状动脉中G蛋白结合受体介导的血管收缩

Caroline Lozahic1, Helen Maddock1, Mark Wheatley1

  • 1Research Centre for Health & Life Sciences, Coventry University, Alison Gingell Building, Priory Street, Coventry, CV1 5FB, UK.

Naunyn-Schmiedeberg's archives of pharmacology
|February 7, 2024
PubMed
概括

德克索鲁比化疗通过内素B,血清素1B和血栓素A2的前列腺素受体增加了血管光滑肌肉细胞收缩. 了解这些G蛋白结合受体通路可能有助于减轻多克索鲁比诱导的血管毒性.

关键词:
癌症治疗不良影响的副作用心脏毒性 有关心脏的毒性.冠状动脉微血管功能.冠状动脉微血管功能.德克索鲁比辛是一种多克索鲁比辛.G-蛋白结合受体的受体.血管毒性 血管毒性

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