在埃塞俄比亚东部的精神分裂症患者中,抗精神病药物不服药和相关因素
Fethia Mohammed1, Biftu Geda2, Tesfaye Assebe Yadeta3
1Department of Psychiatry, School of Nursing and Midwifery, College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia. fethia0661@gmail.com.
BMC psychiatry
|February 7, 2024
概括
在埃塞俄比亚精神分裂症患者中,抗精神病药物不服药率很高. 单身状态,酒精,Khat使用和洞察力差等因素增加了不遵守的风险.
科学领域:
- 精神病学和心理健康 精神病学和心理健康
- 公共卫生 公共卫生
- 药理学 药理学是指药理学的学科.
背景情况:
- 抗精神病药物治疗对于治疗精神分裂症和预防复发至关重要.
- 对抗精神病药物的不坚持是精神分裂症护理的一个重大挑战.
- 这项研究探讨了埃塞俄比亚东部的非坚持的流行率和相关因素.
研究的目的:
- 评估埃塞俄比亚东部精神分裂症患者中抗精神病药物不服药率.
- 确定与这一群体中抗精神病药物不服药相关的关键因素.
主要方法:
- 在埃塞俄比亚东部的两个公立医院进行了一项基于机构的横截面研究.
- 从2022年12月到2023年1月收集的数据使用莫里斯基药物坚持评级表和自我报告精神病洞察量表 (ISP).
- 统计分析涉及多步后勤回归来确定调整的几率比率 (AOR) 和95%信心区间 (CI).
主要成果:
- 在44.57%的患者中观察到高比例的不坚持抗精神病药物治疗.
- 与不坚持相关的重要因素包括单身 (AOR=2.48),酒精使用 (AOR=2.00),哈特 (AOR=2.84),以及对疾病缺乏洞察力 (AOR=2.10).
- 这些因素具有统计学意义 (p值≤0.05).
结论:
- 在埃塞俄比亚东部的精神分裂症患者中,抗精神病药物不坚持是普遍存在的.
- 婚姻状况,物质使用 (酒精和Khat) 和不良的疾病洞察力是影响遵守的关键因素.
- 开发针对这些因素的有针对性的干预措施对于改善药物坚持和患者结果至关重要.
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