婴儿和幼儿时期生长和神经认知发育的性别差异
1Department of Women and Children's Health, King's College London, LondonSE1 7EH, UK.
The Proceedings of the Nutrition Society
|February 8, 2024
概括
男孩面临着更高的早期营养不良风险,特别是在粮食不安全期间. 这种脆弱性,可能是由于更高的生物能量需求,对神经发育和健康结果有影响.
科学领域:
- 公共卫生 公共卫生
- 儿科 儿科 儿科
- 发展生物学 发展生物学
背景情况:
- 早期营养不良 (消耗,发育迟缓,体重不足) 构成全球健康风险,影响发病率,死亡率,神经发育和长期结果.
- 一个常见的假设是,尽管有证据表明男性死亡率更高,但女孩对生命早期暴露的脆弱性更大.
- 最近的发现表明,男孩,而不是女孩,在粮食不安全的环境中,营养不良的风险增加,伴有性别特异的神经发育风险.
研究的目的:
- 探索早期营养不良风险中的性别差异.
- 调查观察到男性对营养不良的脆弱性背后的机制.
- 为保护弱势男孩的政策考虑提供信息.
主要方法:
- 对早期营养不良的性别差异现有证据的审查.
- 分析可能影响性别特异性风险的生物学和社会因素.
- 考虑对公共卫生计划和政策的影响.
主要成果:
- 男孩在早期生活中表现出营养不良的风险增加,特别是在粮食不安全的情况下.
- 这种脆弱性似乎独立于青男孩的社会因素,这表明有生物学基础.
- 对于男孩的生长和维持来说,更高的能量需求可能会在营养困难期间导致营养不良.
结论:
- 新出现的证据凸显了男孩在早期生活中对营养不良的严重脆弱性.
- 生物因素,如不同的能源需求,可能是这种性别特异性风险的基础.
- 政策和方案干预应考虑这些发现,以更好地保护男孩的健康和发展.
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