一个温暖的温度释放的负反循环微调了Arabidopsis中的PIF4介导的热态生成
Hui Li1, Mande Xue1, Huairen Zhang2
1Key Laboratory of Seed Innovation, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China; University of Chinese Academy of Sciences, Beijing, China.
Plant communications
|February 8, 2024
概括
高温会通过激活PIF4来触发植物茎的延长. 一个涉及GI,ELF3和HY5的负反循环微调了这种生长反应,确保植物适应温暖.
科学领域:
- 植物生物学 植物生物学
- 分子生物学分子生物学
- 遗传学 是一个遗传学.
背景情况:
- 植物表现出热敏的生长,根据环境温度调整延长.
- 植物染色体交互因子4 (PIF4) 是Arabidopsis中高温诱导的茎延长的一个关键调节器.
研究的目的:
- 阐明植物热敏生长背后的分子机制.
- 研究GI,TOC1,ELF3和HY5在调节PIF4活动和植物热态生成中的作用.
主要方法:
- 在Arabidopsis.中进行遗传分析.
- 研究基因转录和蛋白质活性.
- 染色体免疫沉以研究色素变体丰富.
主要成果:
- 高温促进夜间的胃肠道转录,这对TOC1转录至关重要.
- 胃肠道抑制PIF4,防止过度热敏生长,这一过程部分依赖TOC1.1.
- ELF3和HY5抑制胃肠道转录和PIF4活动;温度升高使它们失活/降解,释放抑制.
- PIF4进一步激活胃肠道转录,创建一个负反循环,微调PIF4活动.
- ELF3,HY5和PIF4通过在GI位点的H2A.Z丰富影响GI转录.
结论:
- 负反循环的热释放微妙地调整了植物热态生成.
- GI,PIF4,ELF3和HY5之间的相互作用,由质子变异H2A.Z调节,对于植物的温度感知和生长适应至关重要.
相关概念视频
Cell Signaling Feedback Loops
6.3K
Positive and negative feedback loops are crucial for regulating biological signaling systems. These feedback loops are processes that connect output signals to their inputs.
Negative feedback loops
Most signaling systems have negative feedback loops that can perform different functions such as output limiter, and adaptation.
Output limiter
Upon receiving an input signal, the cellular response rapidly increases until a threshold is reached. Beyond this threshold, a negative feedback loop...
Negative feedback loops
Most signaling systems have negative feedback loops that can perform different functions such as output limiter, and adaptation.
Output limiter
Upon receiving an input signal, the cellular response rapidly increases until a threshold is reached. Beyond this threshold, a negative feedback loop...
6.3K
Feedback Inhibition
53.9K
Biochemical reactions are occurring constantly in cells, converting starting substances to different products, usually with the help of enzymes that speed the reactions. Without enzymes, it would take far too long for most reactions to occur to be useful to the cell!
53.9K
Cell Signaling in Plants
5.6K
Plant cells communicate to coordinate their cycle of growth, flowering and fruiting, and activities in roots, shoots, and leaves in response to the changing environmental conditions. Plant signaling is distinct from animal signaling. Plants primarily utilize enzyme-linked receptors, whereas the largest class of cell-surface receptors in animals are G-protein coupled receptors (GPCRs). Unlike animals, receptor tyrosine kinases are rare in plants. Instead, plants have a diverse class of...
5.6K
Responses to Heat and Cold Stress
13.5K
Every organism has an optimum temperature range within which healthy growth and physiological functioning can occur. At the ends of this range, there will be a minimum and maximum temperature that interrupt biological processes.
13.5K
Feedback Loops
57.5K
In most cases, excessive hormone production is prevented by negative feedback—a loop that starts with a stimulus inducing the release of a particular substance, like a hormone, to maintain a certain level before triggering a signal that results in a decrease in further release of the hormone.
57.5K
TGF - β Signaling Pathway
7.4K
The TGF-β signaling pathway regulates cell growth, differentiation, adhesion, motility, and development. TGF-β ligands that induce TGF-β signaling are synthesized in their latent form. Several proteases or cell surface receptors such as integrins act upon the latent form, releasing the active ligand. There are three types of mammalian TGF-βs: (TGF-β1, TGF-β2, and TGF-β3) that bind as homodimers or heterodimers to TGF-β receptors. The TGF-β receptors...
7.4K


