在患有早期至中度青光瘤的患者中,阅读表现的结构功能关系
Serpil Akar1, Oya Tekeli2, Aysun Idil3
1Department of Ophthalmology, Baskent University, Istanbul Hospital, Istanbul, Turkey.
European journal of ophthalmology
|February 8, 2024
概括
与健康个体相比,初级开角玻璃眼 (POAG) 患者的阅读速度和表现有所降低. 这种下降与视网膜内部的稀薄有关,这表明阅读困难可能在青光眼早期出现.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼研究研究 玻璃眼研究
- 视觉神经科学是一种神经科学.
背景情况:
- 主要开角青光眼 (POAG) 是不可逆转失明的主要原因.
- 早期发现和了解功能缺陷对于管理POAG至关重要.
- 阅读能力是日常功能的一个关键方面,可能会受到绿眼病的影响.
研究的目的:
- 为了评估轻度至中度POAG.患者的阅读表现.
- 调查阅读能力与各种眼科参数之间的相关性,包括视野 (VF),微观测量和光学连贯性断层扫描 (OCT).
主要方法:
- 在30名POAG患者和21名对照中,使用明尼苏达州阅读敏度图 (MNREAD) 评估了阅读表现.
- 视觉现场测试使用汉弗里现场分析仪 (HFA) 进行.
- 光学连贯断层扫描 (OCT) 用于测量视网膜神经纤维层厚度 (RNFLT),视神经头部 (ONH) 参数,以及质细胞内状层厚度 (GCIPLT).
主要成果:
- POAG患者的最大阅读速度 (MRS) 和阅读可访问性 (RA) 显著降低.
- 减少的MRS与更薄的平均和特定象限的质细胞内形层厚度 (GCIPLT) 相关.
- 视野,微观度和ONH/RNFLT参数与阅读性能没有相关性.
结论:
- 与健康对照组相比,POAG患者的阅读表现受损.
- 阅读速度与黄斑GCIPLT下降之间的关联表明,阅读困难可能在POAG的早期阶段表现出来.
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