对心身干预创伤后应激障碍的随机对照试验:一个系统的审查
Josh Kaplan1, Vanessa C Somohano2, Belle Zaccari2,3
1Department of Neurology, Oregon Health & Science University, Portland, OR, United States.
Frontiers in psychology
|February 8, 2024
概括
心身干预 (MBI) 在创伤后应激障碍 (PTSD) 中表现有前途. 基于运动的干预措施 (MoBIs) 有适度的证据,而基于正念的干预措施 (MiBIs) 和基于冥想的干预措施 (MMIs) 由于研究的局限性,证据较低.
科学领域:
- 精神病学和行为科学
- 补充和替代医学 补充和替代医学
背景情况:
- 心身干预 (MBI) 包括基于正念 (MiBIs),基于冥想和咒语 (MMIs) 和基于运动 (MoBIs) 的方法.
- 初步证据表明,MBI可能会改善创伤后应激障碍 (PTSD) 的症状.
- 现有审查强调了对比条件,测量一致性和客观结果的局限性.
研究的目的:
- 对MBI治疗PTSD的高质量证据进行更新的系统审查.
- 评估相关随机对照试验 (RCT) 中偏差风险.
- 综合当前关于不同类型的MBI对PTSD疗效的证据.
主要方法:
- 系统搜索多个数据库 (2018年6月-2022年6月) 使用AHRQ资助的PTSD-Repository的证据表.
- 包括26个符合特定标准的随机对照试验 (RCT).
- 从PTSD-Repository证据表中提取数据和偏见风险评估.
主要成果:
- 对MiBIs和MMIs的证据强度被评为低,原因是发现不一致,比较器问题以及偏差风险高.
- 对MoBIs的证据强度被评为中度,在更多的研究和参与者中发现了一致的积极结果.
- 在包括的26项研究中,只有两项使用了客观结果指标.
结论:
- 基于运动的干预措施显示PTSD症状改善的适度证据.
- 需要进一步的研究来解决研究设计,比较器和对MiBIs和MMIs的客观措施的局限性.
- 这些发现为未来的研究方向和MBI在PTSD治疗中的临床应用提供了信息.
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