在患有慢性鼻炎的患者中,外周异敏症,JESREC评分和嗅觉功能障碍之间的关联
Ling Zhang1, Haifeng Li1, Tao Wang1
1Department of Otorhinolaryngology, The First People's Hospital of Changzhou, The Third Affiliated Hospital of Soochow University, Soochow University, Changzhou, China.
Frontiers in immunology
|February 8, 2024
概括
周围异性和高的日本抗菌异性慢性鼻炎 (JESREC) 疫情调查得分与慢性鼻炎 (CRS) 患者的嗅觉功能障碍有关. 如果JESREC评分为5.5或更高,则表示存在重大风险.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 过敏和免疫学 过敏和免疫学
- 流行病学 流行病学
背景情况:
- 慢性鼻炎 (CRS) 是一种常见的疾病,影响鼻通道和鼻.
- 嗅觉功能障碍或嗅觉障碍是CRS患者经常出现的,令人衰弱的症状.
- 边缘性乙和日本抗性乙性慢性鼻炎流行病学调查 (JESREC) 评分是疾病严重程度和治疗反应的潜在指标.
研究的目的:
- 调查CRS患者的外周性异osinophilia,JESREC分数和嗅觉功能障碍之间的关联.
- 确定JESREC评分的预测准确度和最佳切断点,用于识别CRS中的嗅觉功能障碍.
主要方法:
- 这是一项涉及354名CRS患者的横截面,回顾性研究.
- 嗅觉功能使用12项Sniffin' Sticks测试进行评估.
- 使用多变量逻辑回归和接收器运行特征 (ROC) 曲线分析来评估关联并推导切割值.
主要成果:
- 在研究的CRS患者中,嗅觉功能障碍的患病率为46.3%.
- 周围的好色素 (OR 1.25) 和较高的JESREC评分 (OR 1.31) 与嗅觉功能障碍有显著的关联.
- 杰斯雷克得分显示曲线下的面积为0.778,预测嗅觉功能障碍的切断值为5.5.
结论:
- 周围的好色素和较高的JESREC分数是CRS嗅觉功能障碍的重要危险因素.
- 一个JESREC得分为6或更高的值得密切关注,因为它与嗅觉功能障碍的风险增加有关.
- 杰斯雷克评分是预测CRS患者嗅觉功能障碍的一个有价值的工具.
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