出生时感官运动视觉连接组梯度的发展预测了2岁时的神经认知结果
Yunman Xia1,2,3,4, Jianlong Zhao1,2,3, Yuehua Xu1,2,3
1State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing 100875, China.
iScience
|February 8, 2024
概括
大脑连接体梯度在早产婴儿中很早就出现,显示着持续向长期类似模式的发展. 这些早期的大脑组织原理预测了儿童以后的认知和语言技能.
科学领域:
- 神经科学是一个神经科学.
- 发育神经科学的发展神经科学.
- 脑部成像 脑部成像
背景情况:
- 功能连接体梯度是大脑中关键的组织原则.
- 了解早期大脑发育对于预测认知结果至关重要.
研究的目的:
- 研究早产和晚产婴儿功能连接体梯度的发展.
- 将早期连接体梯度与以后的认知成长联系起来.
主要方法:
- 在31-42周月经后的婴儿中使用无任务功能性MRI.
- 分析的重点是全球和焦点梯度的发展.
- 使用开发人类连接组项目数据集验证了结果.
主要成果:
- 主要的感觉运动到视觉梯度存在于晚期早产婴儿中,并且随着年龄的增长而演变.
- 全球梯度指标随着月经后年龄的增加而增加.
- 出生时的早期连接体梯度预测了2年的认知和语言结果.
结论:
- 功能连接体梯度很早就出现,并遵循可预测的发育轨迹.
- 早期的大脑连接体组织与产后认知发育有关.
- 这些发现为早期大脑发育的基本规则提供了洞察力.
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