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Updated: Jul 4, 2025

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PARP1凝结分离分区DNA修复蛋白,并增强DNA结合

Christopher Chin Sang1, Gaelen Moore1, Maria Tereshchenko1

  • 1Department of Biochemistry, University of Toronto, Toronto, ON, M5S 1A8, Canada.

bioRxiv : the preprint server for biology
|February 8, 2024
PubMed
概括

聚 ((ADP-ribose) 聚合酶1 (PARP1) 形成DNA依赖的凝聚物,这些凝聚物会招募DNA修复蛋白. PARylation 增强了这些凝聚物,促进了 DNA 修复和结合.

关键词:
在ADP-ribosylation过程中.修复DNA的修复DNA的修复PARP1 的第一部分生物分子凝聚剂是生物分子凝聚剂.阶段分离的阶段分离.后翻译修改 (PTMs) 是指翻译后的修改.单链断裂修复 (SSBR) 是一种单链断裂修复.

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