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Updated: Jul 4, 2025

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
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大型图书馆对接大麻素-1受体激动剂,副作用减少

Tia A Tummino, Christos Iliopoulos-Tsoutsouvas, Joao M Braz

    bioRxiv : the preprint server for biology
    |February 8, 2024
    PubMed
    概括

    研究人员通过对接数百万个分子来发现新的大麻素-1受体 (CB1R) 激活剂,发现了新的大麻素化学型. 这导致了一种具有强烈止痛作用和广泛的治疗窗口的强有力的新激动剂,这表明了更安全的疼痛治疗的潜力.

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