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Updated: Jul 4, 2025

Oct4GiP Reporter Assay to Study Genes that Regulate Mouse Embryonic Stem Cell Maintenance and Self-renewal
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Oct4GiP Reporter Assay to Study Genes that Regulate Mouse Embryonic Stem Cell Maintenance and Self-renewal

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在体细胞重编程过程中,OCT4在胚胎外内皮干细胞 (XEN) 细胞原始体中表达

Alexandra Moauro1,2, Stephanie L Hickey3, Michael A Halbisen3

  • 1Molecular, Cellular and Integrative Physiology Ph.D. Program, Michigan State University, East Lansing, MI, 48824.

bioRxiv : the preprint server for biology
|February 8, 2024
PubMed
概括

在重编程过程中,即使没有Oct4过度表达,也会形成诱导的XEN细胞. 这表明,XEN细胞发育的自然途径是建立多能性的组成部分,反映了早期胚胎发育.

关键词:
胚胎衍生干细胞是胚胎衍生干细胞.胚胎外的内皮内皮.身体细胞重编程体细胞重编程

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Generating iPS Cells from MEFS through Forced Expression of Sox-2, Oct-4, c-Myc, and Klf413:02

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