流感B病毒的NS1蛋白与5'-三酸化dRNA结合,抑制RIG-I激活和宿主抗病毒反应

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Updated: Jul 4, 2025

Affinity Purification of Influenza Virus Ribonucleoprotein Complexes from the Chromatin of Infected Cells
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Affinity Purification of Influenza Virus Ribonucleoprotein Complexes from the Chromatin of Infected Cells

Published on: June 3, 2012

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Ryan Woltz1,2, Brandon Schweibenz2, Susan E Tsutakawa3

  • 1Department of Molecular Biology and Biochemistry, Rutgers, The State University of New Jersey, Piscataway, NJ, 08854, USA.

bioRxiv : the preprint server for biology
|February 8, 2024
PubMed
概括

流感B病毒的NS1B蛋白与5'三酸化双链RNA (5'ppp-dsRNA) 结合,阻断宿主RIG-I抗病毒通路. 这一发现揭示了一个新的免疫逃避策略和抗病毒药物的潜在目标.

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