基因型相关的遗传性反菌可以是一个稳定的微生物群传给后代
Xinwei Zang1, Huizeng Sun1, Mingyuan Xue1
1Institute of Diary Science, College of Animal Sciences, Zhejiang University, Hangzhou 310058, China.
ISME communications
|February 8, 2024
概括
乳牛中的可遗传的乳头细菌具有很高的稳定性,可以从母亲传给后代. 这种垂直传播表明,在几代人之间存在着一致的微生物群落,影响宿主特征.
科学领域:
- 鲁门微生物组研究
- 乳牛遗传学 乳牛遗传学 乳牛遗传学
- 微生物生态学 微生物生态学
背景情况:
- 一些肠微生物表现出遗传性,影响宿主表型.
- 这些可遗传的乳头细菌在几代人间的垂直传播尚未得到充分理解.
研究的目的:
- 为了研究可遗传的反菌从母牛向后代的垂直传播.
- 为了确定宿主遗传关联与遗传细菌的丰度.
主要方法:
- 在母牛和它们的后代之间比较肠细菌组成.
- 分析宿主基因型及其与遗传细菌丰度的相关性.
- 评估几代人之间的微生物功能稳定性.
主要成果:
- 可遗传的小肠细菌在母体和后代之间表现出比非可遗传的细菌更高的组成相似性.
- 五种宿主基因型与两种可遗传的细菌物种,即*Pseudoscardovia*和*p-251-o5*的相对丰度有关.
- 与非遗传功能相比,预测的遗传性微生物功能在几代人之间更稳定.
结论:
- 可遗传的小牛体细菌表现出显著的稳定性,在奶牛中从母体垂直传播给后代.
- 宿主基因在塑造特定遗传性小吃细菌的丰富性方面发挥着重要作用.
- 这种可遗传的乳头微生物的代代稳定性表明,它在几代人之间对宿主表型产生了一致的影响.
相关概念视频
Bacterial Flora of the Large Intestine
449
The gut microbiome is formed by a vast and diverse community of bacteria that colonizes our large intestine. These bacteria start residing in the gut from birth and continue diversifying throughout life, influenced by factors such as diet, lifestyle, and stress. The gut bacterial community also includes bacteria from food and those that enter the colon through the anus.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
449
Anatomy of the Intestines
72.0K
Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
72.0K
Background and Environment Affect Phenotype
6.5K
Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
6.5K
Animal Mitochondrial Genetics
7.6K
Among all the organelles in an animal cell, only mitochondria have their own independent genomes. Animal mitochondrial DNA is a double-stranded, closed-circular molecule with around 20,000 base pairs. Mitochondrial DNA is unique in that one of its two strands, the heavy, or H, -strand is guanine rich, whereas the complementary strand is cytosine rich and called the light, or L, -strand. Compared to nuclear DNA, mitochondrial DNA has a very low percentage of non-coding regions and is marked by...
7.6K
Law of Segregation
65.9K
When crossing pea plants, Mendel noticed that one of the parental traits would sometimes disappear in the first generation of offspring, called the F1 generation, and could reappear in the next generation (F2). He concluded that one of the traits must be dominant over the other, thereby causing masking of one trait in the F1 generation. When he crossed the F1 plants, he found that 75% of the offspring in the F2 generation had the dominant phenotype, while 25% had the recessive phenotype.
65.9K
Probability Laws
40.8K
Overview
40.8K


