数字形态与光学显微镜相比:关于报告骨髓吸收的验证研究
G Zini1,2, P Chiusolo1,2, E Rossi1,2
1Department of Radiological and Hematological Sciences, Hematology Section, Catholic University of Sacred Heart Rome, Rome, Italy.
International journal of laboratory hematology
|February 8, 2024
概括
数字骨髓吸入评估与传统显微镜一样有效. 这项技术提供了诸如减少工作量和改善图像共享等优势,以提高诊断准确度.
科学领域:
- 血液学 血液学 血液学
- 数字病理学数字病理学
- 医疗成像医学成像
背景情况:
- 传统的骨髓吸入评估依赖于手动显微镜.
- 数字病理学为改善工作流程和数据管理提供了潜力.
研究的目的:
- 评估骨髓吸收的数字图像评估的有效性和可靠性.
- 将数字形态学家的评估与经典的显微镜评估进行比较.
主要方法:
- 使用整体幻灯片成像 (WSI) 系统扫描了180个骨髓吸附涂抹.
- 分析了数字和显微镜读数之间的统计可比性和偏差风险.
主要成果:
- 数字和显微镜评估显示,细胞群体的数量和质量结果相似.
- 在这两种方法中都始终确定了失塑性特征.
- 细胞性评估是相当的,在数字分析中略有趋向于"正常".
结论:
- 对骨髓吸收物的数字评估产生了与传统显微镜可比的结果.
- 数字成像提高了诊断中的效率,可重复性和数据共享.
- 常规使用数字骨髓吸收评估不会影响诊断质量.
相关概念视频
01:22Overview of Microscopy Techniques
10.3K
The early pioneers of microscopy opened a window into the invisible world of microorganisms. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes that leveraged nonvisible light, such as fluorescence microscopy that uses an ultraviolet light source and electron microscopy that uses short-wavelength electron beams. These advances significantly improved magnification, image resolution, and contrast. By comparison, the...
10.3K
01:18Imaging Biological Samples with Optical Microscopy
4.7K
Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
4.7K