相关实验视频
Updated: Jul 4, 2025
03:37
Intravitreal Injections in the Ovine Eye
Published on: July 5, 2022
3.3K
马类脑膜炎:在一次或两次静脉内低剂量 gentamicin 注射后的结果和不良反应
S Morén1, M Kallberg1, L Strom1
1Equine Clinic, University Animal Hospital, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Equine veterinary journal
|February 8, 2024
概括
慢性脑膜炎的马体内注射低剂量珍塔素 (IVGI) 显示出41%的阳性结局率. 然而,视网膜退化等并发症发生在22%的眼睛中,需要仔细考虑这种治疗.
科学领域:
- 兽医眼科医生 兽医眼科医生
- 马类医学 马类医学
- 药理学 药理学是指药理学的学科.
背景情况:
- 马的慢性脑膜炎会导致视力受损或失明.
- 目前的治疗方法通常需要长期服用药物,可能会产生副作用.
- 用低剂量 gentamicin (IVGI) 进行静脉内注射正在研究马匹持续性脑膜炎的治疗.
研究的目的:
- 为了评估低剂量静脉内 gentamicin 注射的结果和长期并发症 (IVGI) 在瑞典马患有慢性脑膜炎.
- 评估一两种IVGI治疗方法在治疗马类慢性脑膜炎的有效性.
主要方法:
- 在2016年至2021年期间被诊断患有慢性脑膜炎的马匹的回顾性病例系列.
- 纳入标准:用4毫克IVGI治疗的马,有些人接受了持续性脑膜炎的第二次注射.
- 积极的结果被定义为控制的卵膜炎,使用极少或不使用抗炎药物.
主要成果:
- 41% (13/32眼) 的马在一次或两次IVGI治疗后取得了积极的结果.
- 并发症包括视网膜退化 (22%的眼睛) 和成熟的白内障 (15.6%的眼睛).
- 由于治疗失败或并发症,在14/32只眼睛中进行了化;一匹马被安乐死.
结论:
- 低剂量IVGI在41%的治疗马眼中产生了积极的结果,主要是前额膜炎.
- 视网膜退化是一个值得注意的并发症,观察到的比例比以前报告的要高 (22%).
- 限制包括小样本规模,回顾性设计和缺乏对照组.
相关概念视频
01:28Angle Closure Glaucoma: Treatment
499
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
499
01:27Open Angle Glaucoma: Treatment
449
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
449
01:25Glaucoma: Overview
571
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
571