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视网母细胞瘤儿童的轨道发育:基于成像的研究

Shir Forer¹, Guy J Ben Simon^2,3,4, Gahl Greenberg^3,5

¹Hadassah Faculty of Medicine, The Hebrew University, Jerusalem, Israel.

Seminars in ophthalmology

|February 8, 2024

概括

与健康的眼睛相比,接受视网母细胞瘤 (Rb) 治疗的儿童的轨道生长速度较慢. 核化进一步损害了这个轨道的发展,影响了长期的结果.

科学领域:

眼科医生眼科眼科
儿科瘤学儿科瘤学
医疗成像医学成像

背景情况:

视网母细胞瘤 (Rb) 是一种需要治疗的儿童眼癌,可能会影响眼部发育.
了解Rb治疗对轨道生长的长期影响对于患者护理至关重要.

研究的目的:

研究视网母细胞瘤 (Rb) 治疗对儿童轨道发育的影响.
为了比较Rb受影响的眼睛与健康眼睛的轨道生长.

主要方法:

在2004年至2020年期间,44名儿童接受Rb治疗的回顾性病例系列.
利用3D图像处理软件来评估轨道体积和测量.
在最后一次随访时,对Rb受影响的眼睛和健康的眼睛之间的轨道生长差异进行比较.

主要成果:

轨道体积仅在健康的眼睛中与年龄正相关 (p=.03).
单边Rb病例中受影响的轨道呈现出比健康眼睛更小的水平,垂直和深度尺寸 (p<.05).
与保守治疗相比,通过核化处理的轨道显示出显著减少的生长 (p=.017).

结论:

与健康的轨道相比,治疗视网母细胞瘤的儿童的轨道生长速度减少.
核化与轨道生长进展的负面影响有关.

关键词:

轨道成长的轨道成长.轨道体积轨道体积轨道体积视网膜母细胞瘤 (Retinoblastoma) 是一种

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