与MDMA和迷幻药物相关的攻击性行为:叙述性审查
Negar Sayrafizadeh1, Nicole Ledwos1, M Ishrat Husain2,3
1Centre for Complex Interventions, Centre for Addiction and Mental Health (CAMH), Toronto, ON, Canada.
Acta neuropsychiatrica
|February 8, 2024
概括
血清醇类迷幻药和MDMA对侵略性的影响是复杂的. 研究表明,研究结果各不相同,一些研究表明侵略性增加,而另一些研究表明保护作用,需要进一步调查.
科学领域:
- 神经科学是一个神经科学.
- 心理药理学 心理药理学
- 行为科学 行为科学
背景情况:
- 单胺神经递质与攻击性有关,特别是受到非法物质影响时.
- 现有的文献表明,并非所有非法物质都会诱发侵略,而迷幻药是一种显著的例外.
研究的目的:
- 为了研究血清醇类迷幻药物和3,4-甲基二氧化甲胺 (MDMA) 之间对侵略行为的关联.
- 综合当前关于这些物质与侵略之间的关系的研究.
主要方法:
- 使用PubMed和PsycINFO数据库进行了叙事审查.
- 搜索了原创的,同行评审的文章,评估了胺类精神药物和MDMA对侵略行为的影响.
- 遵守系统审查和元分析 (PRISMA) 准则的首选报告项目.
主要成果:
- 17篇文章符合纳入标准,其中14篇专注于MDMA,3篇专注于血类迷幻药物.
- 关于迷幻药对攻击性的影响的发现是混合的,一些研究报告增加了攻击性,而另一些研究表明有保护作用.
- 确定的局限性包括对迷幻药物的各种定义,缺乏标准化的结果措施,以及不受控制的混因素.
结论:
- 需要进一步的研究,才能充分了解胺类精神药物和MDMA对侵略行为的影响.
- 随着迷幻药物研究领域的不断扩大,需要对其对侵略的影响进行持续评估.
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