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Updated: Jul 4, 2025

A Protocol for Computer-Based Protein Structure and Function Prediction
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一个由人工智能生成的蛋白质基因尺度数据集,用于预测细胞 Mnemiopsis leidyi 的蛋白质结构

R Travis Moreland1, Suiyuan Zhang1, Sofia N Barreira1

  • 1Center for Genomics and Data Science Research, Division of Intramural Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA.

Proteomics
|February 8, 2024
PubMed
概括

研究人员通过计算预测了Mnemiopsis leidyi虫的蛋白质结构,使用AlphaFold.生成了15333个预测. 这些新的蛋白质结构预测增强了Mnemiopsis作为早期动物进化和人类健康研究的模型.

关键词:
进化生物学是进化的生物学.蛋白质结构预测 蛋白质结构预测结构注释结构注释视觉化的可视化

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Conserved Binding Sites

Many proteins’ biological role depends on their interactions with their ligands, small molecules that bind to specific locations on the protein known as ligand-binding sites. Ligand-binding sites are often conserved among homologous proteins as these sites are critical for protein function.
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