左心室辅助装置候选人的右心室功能障碍:是时候改变我们的前景了吗?
Carlotta Sciaccaluga1, Maria Cristina Procopio2, Luciano Potena3
1Department of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy. carlotta.sciaccaluga@gmail.com.
Heart failure reviews
|February 8, 2024
概括
左心室辅助装置 (LVAD) 的使用正在增加,但右心力衰竭仍然是死亡率的关键预测因素. 植入前右心室 (RV) 评估缺乏共识,影响患者选择和结果.
科学领域:
- 心脏病学 心脏病学
- 心血管外科心血管外科
- 医疗器械 医疗器械
背景情况:
- 由于供体短缺,左心室辅助器件 (LVAD) 越来越多地用于晚期心力衰竭.
- 右心力衰竭是LVAD接受者的死亡率的重要预测因素.
- 目前的植入前右心室 (RV) 评估方法显示出高度的异质性,并且缺乏关于最佳参数和切线值的共识.
研究的目的:
- 在LVAD植入之前审查当前关于右心室功能的作用和评估的证据.
- 突出目前VR评估参数的变化,并探索未来的诊断工具.
- 总结围绕手术的治疗策略,以减少RV失效的发生率,特别是在RV功能模两可的情况下.
主要方法:
- 在LVAD植入的背景下评估右心室功能的研究的综合文献综述.
- 用于RV评估的临床,实验室,心声和侵入性血液动力学参数的分析.
- 检查新兴的诊断技术和术前管理策略.
主要成果:
- 在LVAD之前评估RV功能的预测指标和切断值存在显著的异质性.
- 这种变异性使得在LVAD后对VR衰竭的高风险患者的鉴定变得复杂.
- 技术的进步使得即使在没有最佳VV功能的患者中,也可以考虑使用LVAD.
结论:
- 标准化和可靠的植入前VR评估对于优化LVAD结果至关重要.
- 需要进一步研究新型诊断工具和精细的术后管理,以减轻RV故障风险.
- 解决RV功能评估挑战对于扩大LVAD治疗的好处至关重要.
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