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Updated: Jul 4, 2025

Transfer of Manipulated Tumor-associated Neutrophils into Tumor-Bearing Mice to Study their Angiogenic Potential In Vivo
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组织特异性重编程导致血管性中性粒细胞专业化和结直肠癌中的瘤血管化

Triet M Bui1, Lenore K Yalom1, Edward Ning1

  • 1Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

The Journal of clinical investigation
|February 8, 2024
PubMed
概括

与瘤相关的中性粒细胞 (TAN) 通过调节血管生长来促进结直肠癌 (CRC) 的血管化. 抑制TAN或MMP14有效地减少了瘤生长,这表明了CRC的新治疗策略.

关键词:
细胞免疫反应的细胞免疫反应.结肠直肠癌是一种癌症.胃肠病学 胃肠病学免疫学 免疫学 免疫学中性粒细胞中的中性粒细胞.

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