夜班工作和不规则的月经周期:8年的随访队列研究
K Kim1,2, M Y Lee3, Y Chang1,4,5
1Department of Occupational and Environmental Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Occupational medicine (Oxford, England)
|February 8, 2024
概括
夜班工作增加了女性工人的不规则月经周期的风险. 这种关联在现有和新病例中都被观察到,无论睡眠质量,工作时间或肥胖程度如何.
科学领域:
- 职业健康 职业健康 职业健康
- 生殖内分泌学 生殖内分泌学
- 流行病学 流行病学
背景情况:
- 不规律的月经是女性的重大健康问题.
- 夜班工作和月经不规则之间的联系尚未得到充分证实.
- 之前的研究已经产生了关于这种关联的有争议的发现.
研究的目的:
- 调查夜班工作与女性工人的不规则月经周期之间的关联.
- 探索睡眠质量,工作时间和肥胖对这种关系的潜在缓解影响.
主要方法:
- 涉及女性工人的横截面和纵向研究设计 (N=87,147和N=41,516分别).
- 数据是通过关于夜班工作,工作时间,睡眠质量和月经周期特征的自我管理问卷收集的.
- 不规则的月经定义为自我报告的不规则性或周期长度≥36天.
- 统计分析包括多变量逻辑回归和Cox比例危险模型.
主要成果:
- 夜班工作与常见的不规则月经周期有显著的关联 (OR=1.26,95% CI 1.2-1.33).
- 夜班工作也与6年来发生的不规则月经周期有关 (aHR=1.95,95% CI 1.61-2.35).
- 在按睡眠质量,工作时间或肥胖而分层时,没有发现显著的相互作用.
结论:
- 夜班工作独立地与患有和发生不规则月经周期的风险增加有关.
- 观察到的关联是强大的,并没有受到睡眠质量,工作时间或肥胖的显著改变.
- 调查结果强调了在生殖健康方面考虑职业暴露的重要性.
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