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在30天的老年患者中,抽出与抽出冠状动脉旁路移植:倾向性得分匹配研究

Chen Wang¹, Yefan Jiang², Qingpeng Wang³

¹Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.

Postgraduate medical journal

|February 8, 2024

概括

无冠状动脉旁路移植 (OPCABG) 对老年患者有好处,降低功能衰竭和出血并发症的风险. 这种方法对于这个人口群体来说,是一种可行的替代品,而不是动冠状动脉旁路移植 (ONCABG).

科学领域:

心血管外科心血管外科
老年医学老年医学
手术结果研究研究.

背景情况:

老年患者面临更高的风险与传统的动冠状动脉旁路移植 (ONCABG).
无冠状动脉旁路移植 (OPCABG) 被探索为这种高风险群体的潜在更安全的替代方案.

研究的目的:

在接受冠状动脉旁路移植的老年患者中,评估OPCABG与ONCABG相比的好处.
在接受OPCABG与ONCABG的老年人中评估术后发病率和死亡率.

主要方法:

对511名老年患者 (≥65岁) 进行首次隔离冠状动脉旁路移植的回顾性分析 (2015年1月至2021年1月).
倾向性得分匹配用于创建ONCABG (173名患者) 和OPCABG (173名患者) 的可比组.
与匹配的ONCABG和OPCABG队列之间的30天术后发病率和死亡率的比较.

主要成果:

在OPCABG组中,不完全再血管化的比率更高 (13.9%对6.9%,P=.035).
OPCABG显著降低了术后功能衰竭的风险 (15.0%与30.1%,P=.001) 和因出血而重新手术的风险 (0.0%与3.5%,P=.030).
两组之间没有观察到早期死亡率,心肌梗塞或中风的显著差异.

结论:

无冠状动脉旁路移植 (OPCABG) 是适合老年患者的替代性复血管化策略.
在老年人中,OPCABG表明早期术后功能衰竭和出血再手术的风险降低.

关键词:

冠状动脉绕道移植冠状动脉绕道移植年长的老人老年人老年人.的关闭-的关闭在上 - .倾向性得分匹配的比分匹配

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