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一种新型的长效双GLP-1/GIP受体激动剂的设计

Yuanzhen Dong1, Jinhua Zhang2, Hongjiang Xu3

  • 1China State Institute of Pharmaceutical Industry, 201203 Shanghai, China; Shanghai Duomirui Biotechnology Ltd, 201203 Shanghai, China.

Bioorganic & medicinal chemistry
|February 8, 2024
PubMed
概括

一种新的双GLP-1/GIP受体激动剂D314在治疗2型糖尿病和肥胖方面显示出有前途的结果. 这种新型化合物表现出与蒂尔泽帕提德 (tirzepatide) 相当的疗效,有可能每周服用一次.

关键词:
作为一个协同激进分子.在GIP的基础上,GIP是GIP.这就是GLP-1.长效的功效 长效的功效肥胖问题 肥胖问题这就是T2DM.

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