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将定量T1rho加权成像添加到传统的MRI中,提高了区分恶性和良性乳腺病变的特异性和灵敏度

Lu Wang¹, Xiaoxia Wang¹, Fujie Jiang¹

¹Department of Radiology, Chongqing University Cancer Hospital, Chongqing Key Laboratory for Intelligent Oncology in Breast Cancer (iCQBC), Chongqing 400030, China.

Magnetic resonance imaging

|February 8, 2024

概括

T1rho加权成像有效地区分恶性和良性乳腺病变. 将T1rho与明显扩散系数 (ADC) 和达到峰值的时间 (TTP) 结合起来,可显著提高诊断准确度,为乳腺癌检测提供了传统MRI的宝贵补充.

科学领域:

放射学放射学是一门学科.
在瘤学瘤学.
医疗成像医学成像

背景情况:

区分恶性和良性乳腺病变对于适当的患者管理至关重要.
传统的MRI技术在实现高诊断准确性方面存在局限性.

研究的目的:

评估T1rho加权成像在区分恶性和良性乳腺病变的可行性.
评估T1rho加权成像对传统MRI参数的诊断附加值.

主要方法:

有望招募113名乳腺病变的妇女.
获得手术前T1rho加权成像,扩散加权成像 (DWI) 和动态对比增强MRI (DCE-MRI).
使用ROC曲线分析,在良性和恶性群体之间比较T1rho值,明显扩散系数 (ADC) 和DCE-MRI参数 (例如达到峰值的时间).

主要成果:

与恶性病变 (72.18 ± 16.37 ms) 相比,良性病变 (92.61 ± 22.10 ms) 的平均T1rho值显著更高 (P < 0.001).
恶性病变的ADC和高峰时间 (TTP) 值低于良性病变 (所有P<0.001).
结合T1rho,ADC和TTP,AUC达到0.896,敏感度为81.0%,特异性为87.1%,显著优于单独使用ADC和TTP.

结论:

T1rho加权成像是一种可行的MRI技术,用于区分恶性和良性乳腺病变.
结合T1rho,ADC和TTP可以提高诊断性能,特别是特异性和灵敏性.
在T1rho加权成像显示承诺作为常规MRI的补充工具在乳腺病变的特征.

关键词:

乳腺新生体的形成.差异诊断是一种差异诊断.磁共振成像技术磁共振成像技术在T1rho-weighted成像中使用T1rho-weighted成像.

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Magnetic Resonance Imaging

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