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Updated: Jul 4, 2025

Genome-Wide Analysis of DNA Methylation in Gastrointestinal Cancer
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Genome-Wide Analysis of DNA Methylation in Gastrointestinal Cancer

Published on: September 18, 2020

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氨酸甲基化依赖的cGAS稳定性促进非小细胞肺癌细胞的增殖

Xiangxiang Liu1, Weiguang Zheng2, Lian Zhang3

  • 1The Key Laboratory of Molecular Epigenetics of Ministry of Education (MOE), Northeast Normal University, Changchun, 130024, China.

Cancer letters
|February 8, 2024
PubMed
概括

蛋白质氨酸甲基转移酶1 (PRMT1) 通过甲基化稳定循环GMP-AMP合成酶 (cGAS),促进非小细胞肺癌 (NSCLC) 细胞增殖. 这个PRMT1-cGAS-USP7轴为NSCLC提供了一个新的治疗点.

关键词:
在 AKT 路径上.氨酸甲基化的阿尔金因.在NSCLCLC中,我们可以看到.在PRMT1中,cGAS 是一个气体.

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