[翻译文章]神经沙丘病症患者的特定皮肤病变
J Marcoval1, A Iriarte2, G Rocamora2
1Servicio de Dermatología, Hospital Universitari de Bellvitge, Barcelona, Spain.
Actas dermo-sifiliograficas
|February 8, 2024
概括
特定的皮肤病变出现在超过四分之一的神经类病患者身上. 识别这些皮肤表现,如黄斑状病变和斑块,可以帮助加快诊断这种中枢神经系统疾病.
科学领域:
- 神经学 神经学
- 皮肤病学 皮肤病学
- 免疫学 免疫学 免疫学
背景情况:
- 神经类症是一种罕见但严重的中枢神经系统疾病.
- 它可以导致严重的长期健康问题.
- 皮肤表现在 Sarcoidosis 中很常见,但它们在神经 Sarcoidosis 中的诊断作用不太了解.
研究的目的:
- 在被诊断为神经类症的患者中分析特定皮肤病变的存在和诊断效用.
- 为了关联神经和皮肤病变类型.
主要方法:
- 追溯分析58名确诊神经类固醇症的患者.
- 审查神经学和皮肤学发现,包括病变类型.
- 评估皮肤病变相对于神经类病诊断的时间.
主要成果:
- 16名患者 (27.6%) 呈现了特定的皮肤病变.
- 观察到的神经病变包括神经病变,脑膜,脑膜和周围神经的参与.
- 常见的皮肤病变是黄斑和斑块的病变和斑块;还注意到痕类样症.
- 在13名患者中,在神经类症诊断时存在特定的皮肤病变.
结论:
- 特定的皮肤病变在显著比例的神经类病患者中存在.
- 鉴定这些皮肤发现可以帮助早期诊断神经类症.
- 皮肤病变的活检可以加快神经类固醇症的诊断过程.
相关概念视频
Skin Diseases and Disorders
5.4K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
5.4K
Skin Cancer
5.2K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
5.2K
Staphylococcal Skin Infections
150
Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
150


