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改变的氧化酸化给IDH1-突变白血病细胞带来了脆弱性:这是可以治疗的吗?

David P Steensma1

  • 1Ajax Therapeutics, Inc., Cambridge, Massachusetts.

Blood cancer discovery
|February 8, 2024
PubMed
概括

这项研究揭示了急性髓性白血病 (AML) 中具有IDH1突变的白血病前干细胞的线粒体氧化酸化系统的独特漏洞. 这一发现可能会为AML患者带来新的向疗法,这些患者在标准治疗后复发.

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