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阿兹提丁通过阻断菌组合来杀死多药耐药的Mycobacterium结核病而没有可检测的抗性

Yixin Cui1, Alice Lanne2, Xudan Peng3

  • 1School of Chemistry, University of Birmingham, Edgbaston, Birmingham, West Midlands B15 2TT, U.K.

Journal of medicinal chemistry
|February 8, 2024
PubMed
概括

新的阿兹提丁衍生物BGAz显示出强大的杀菌活性,对抗药物敏感性和多药耐药结核病 (TB). 这些化合物向细胞包膜生物发生,为结核病治疗提供了一种新的治疗方法.

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