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向DNA2克服了多发性骨髓瘤中的代谢重编程

Natthakan Thongon1, Feiyang Ma2, Natalia Baran1

  • 1Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Nature communications
|February 8, 2024
PubMed
概括

多发性骨髓瘤细胞通过重新连接新陈代谢来抵抗DNA损伤疗法. 准线粒体修复蛋白DNA2会削弱这种抵抗力,揭示了这些癌细胞的新疗法脆弱性.

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