快速Eval帕金森症:一个即时的深度学习辅助的基于视频的在线系统,用于帕金森症运动症状评估
Yu-Yuan Yang1, Ming-Yang Ho2, Chung-Hwei Tai3
1Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, No. 1 Roosevelt Rd. Sec. 4, Taipei, 10617, Taiwan, ROC.
NPJ digital medicine
|February 9, 2024
概括
一个新的深度学习系统,FastEval Parkinsonism,使用视频在诊所以外的帕金森病 (PD) 中评估布拉迪基尼西亚严重程度. 它准确地量化了运动症状,为现实世界患者监测提供了宝贵的工具.
科学领域:
- 神经学 神经学
- 生物医学工程 生物医学工程
- 医疗保健中的人工智能
背景情况:
- 统一帕金森病评级表 (MDS-UPDRS) 评估了勃拉迪基尼西亚,但无法捕捉整天的症状变化.
- 目前评估帕金森病 (PD) 运动症状的方法通常仅限于临床环境.
- 需要在患有PD和相关疾病的个体中对勃拉迪基尼西亚进行客观,持续的监测.
研究的目的:
- 介绍FastEval帕金森症,这是一个基于深度学习的视频系统,用于评估布拉迪基尼西亚严重程度.
- 评估系统在区分帕金森病 (PD),非典型帕金森症 (APD),轻度帕金森症症状 (MPS) 和健康对照 (HCs) 的准确性.
- 通过视频分析确定用于量化PD中的运动性能的关键参数.
主要方法:
- 开发一种使用扩展卷积神经网络的深度学习模型.
- 在PD,APD,MPS和HC组的186个个体的840个指纹视频中训练模型.
- 纳入数据增强技术,以提高模型的稳定性.
- 使用可接受准确度 (AAC) 验证系统性能,并分析频率强度 (FI) 值.
主要成果:
- 深度学习模型在分类运动性能方面实现了 88.0% 和 81.5% 的可接受准确率 (AAC).
- 来自指-食指距离的频率强度 (FI) 值被确定为量化布拉迪基尼西亚的关键参数.
- 该系统证明了使用多角度视频的可用性,通过对300多名PD患者的外部数据集进行验证.
结论:
- FastEval Parkinsonism提供了一种可靠的基于视频的方法,用于评估帕金森病 (PD) 和相关疾病中的布拉迪基尼西亚严重程度.
- 该系统提供客观,可量化的数据,可以补充传统的临床评估.
- 这项技术有可能在现实环境中改善运动症状的监测和管理.
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