在同一天接受双边抗VEGF注射后的内炎:系统性审查
Jakob Bjerager1, Javad Hajari1, Oliver Niels Klefter1,2
1Department of Ophthalmology, Rigshospitalet Glostrup, Valdemar Hansens Vej 1-23, 2600, Glostrup, Denmark.
International ophthalmology
|February 9, 2024
概括
同一天的双边抗VEGF注射对于眼睛疾病似乎是安全的,在对17项研究的审查中没有报告双边内炎病例. 需要进一步的研究来确认内的确切风险.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜疾病 视网膜疾病
- 药理学 药理学是指药理学的学科.
背景情况:
- 静脉内抗VEGF注射是各种视网膜疾病的标准治疗方法.
- 双边治疗往往是必要的,这引发了有关当天使用药物的安全性的问题.
研究的目的:
- 评估在同一天双边静脉内抗VEGF注射后发生内眼炎的风险.
主要方法:
- 在12个数据库中进行了系统的文献搜索.
- 分析了17项涉及138,478次注射的研究的数据.
主要成果:
- 在69,239次双边注射中报告了33例内炎病例.
- 没有观察到双边内眼炎的病例.
- 每次注射内炎的发病率在0%至0.53%之间.
结论:
- 为了方便患者,可以考虑在同一天进行双边抗VEGF注射.
- 建议进行更大规模的研究,以准确确定内的风险.
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