老年人的移植和细胞疗法-MSK方法
Richard J Lin1,2, Parastoo B Dahi3, Beatriz Korc-Grodzicki4
1Adult Blood and Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA. linr@mskcc.org.
Current hematologic malignancy reports
|February 9, 2024
概括
老年人可以从造血细胞移植和血液癌症的细胞免疫治疗中受益. 老年评估有助于优化老年患者的治疗选择和治疗结果.
科学领域:
- 在瘤学瘤学.
- 血液学 血液学 血液学
- 老年病的医生 老年病的医生
背景情况:
- 血液性恶性瘤不成比例地影响老年人,通常呈现为晚期疾病.
- 造血细胞移植 (异质和自身) 和细胞免疫疗法为血液癌症提供治疗潜力.
- 由于独特的健康考虑,老年患者在获得和接受这些密集治疗方面面临挑战.
研究的目的:
- 审查移植和细胞治疗在患有血液恶性瘤的老年人中所带来的益处和改善结果.
- 突出老年评估在选择和优化老年患者接受这些治疗中的作用.
- 为接受这些治疗的老年人提供一种机构方法和早期结果.
主要方法:
- 对老年人血液细胞移植和细胞免疫疗法的现有证据的审查.
- 强调将老年医学评估工具用于患者选择和管理.
- 描述特定的机构协议及其初步结果.
主要成果:
- 证据支持老年人移植和细胞治疗的疗效和改善结果.
- 老年人的评估有助于适当的患者选择和优化治疗.
- 描述的机构方法的早期结果显示出令人鼓舞的结果.
结论:
- 造血细胞移植和细胞免疫疗法是血液恶性瘤的老年人可行的选择.
- 老年人评估对于最大限度地提高这一群体的益处并最大限度地降低风险至关重要.
- 优化治疗策略可以改善老年患者的获取和治疗结果.
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