一种高度溶解的鲁丁形式,可立即解决与戴口罩相关的疾病
Morgane De Tollenaere1, Anaïs Durduret1, Emilie Chapuis1
1Givaudan Active Beauty, Givaudan France SAS, Pomacle, France.
Journal of cosmetic dermatology
|February 9, 2024
概括
一种新的,高度水溶性 rutin 有效地治疗戴口罩引起的皮肤问题,如和发红. 这种可溶性黄胺可减少炎症,氧化应激和超色素,促进皮肤修复,改善舒适度.
科学领域:
- 皮肤病学和化品科学
- 生物化学和药理学 生物化学和药理学
背景情况:
- 在COVID-19大流行期间长时间使用口罩导致,炎症和多颜色等皮肤问题,这是由于改变的微气候和压力造成的.
- 这些与口罩相关的皮肤疾病包括'maskne',粉红发作,红斑和皮肤屏障功能受损.
- 与戴口罩相关的关键问题包括炎症,氧化应激和伤口愈合不良,加剧与有关的疾病.
研究的目的:
- 评估一种新型,高度水溶性 rutin 配方在解决长时间口罩使用引起的皮肤问题方面的有效性.
- 为了研究 rutin 在缓解炎症,氧化应激,多色素和促进皮肤修复方面的潜力.
- 为了克服由rutin水溶性差所带来的配方挑战.
主要方法:
- 进行了体外和体外研究,以评估可溶性鲁丁在皮肤上的生物活性.
- 进行了一项创新的临床试验,志愿者至少戴上2小时的外科口罩.
- 评估了对炎症,氧化应激,伤口愈合,多色素和皮肤红的影响.
主要成果:
- 在体外试验表明,氧化应激和炎症显著减少,并改善了伤口愈合.
- 黑色皮肤外表的ex vivo研究显示,黑色皮肤中的黑色素含量显著下降,这表明皮肤变白.
- 临床试验证实了减少多色素 (棕色斑点),减少红色和血管化,以及志愿者报告的皮肤舒适度提高.
结论:
- 一种高度溶解的 rutin 配方有效地对抗口罩穿戴引起的皮肤问题,包括炎症,氧化应激和多颜色.
- 可溶性 rutin 促进伤口愈合,减少红色,提供了一个有前途的治疗解决方案.
- 这种配方为"maskne"和其他与长时间使用面具相关的皮肤问题提供了快速治疗.
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