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慢性病患者的透导管大动脉置换:一个多中心的回顾性研究
Mohammed Al Jarallah1, Salman Abdulsalam2, Rajesh Rajan1
1Department of Cardiology, Sabah Al Ahmed Cardiac Centre, Al Amiri Hospital, Kuwait City, Kuwait.
Annals of medicine and surgery (2012)
|February 9, 2024
概括
慢性病 (CKD) 在接受过导管大动脉置换 (TAVR) 的患者中显著增加死亡风险. 这项研究强调了在TAVR结果中考虑CKD的重要性.
科学领域:
- 心脏病学 心脏病学
- 腎臟病學 (nephrology) 是一種醫學.
- 公共卫生 公共卫生
背景情况:
- 慢性病 (CKD) 是经过过导管大动脉置换 (TAVR) 的患者经常出现的并发症.
- 有限的研究报告了TAVR患者基线CKD和死亡结果之间的关联.
研究的目的:
- 为了确定TAVR患者中CKD的患病率.
- 分析TAVR患者的手术结果,包括基线CKD和没有基线CKD的患者.
主要方法:
- 在香港43家公立医院进行了回顾性观察性研究.
- 包括在2010年至2019年期间接受TAVR的严重大动脉狭窄患者.
- 根据基线CKD的存在,患者被分组.
主要成果:
- 分析了499名患者;CKD与较高的死亡率相关 (10%对4.1%,P=0.04%).
- 高血压在CKD患者中更为普遍 (82.8%).
- 痛风 (OR=5.96) 和高血压 (OR=2.83) 与慢性功能衰竭 (CRF) 有意义地相关.
结论:
- 基线CKD是在接受TAVR的重症大动脉狭窄患者的长期死亡率的显著预测因素.
- 治疗CKD对于改善TAVR患者的治疗结果至关重要.
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