阴道细菌感染与怀孕结果之间的关系:系统性审查和元分析
Hojjat Rokni1, Amjad Ahmadi2, Yousef Moradi3
1Department of Epidemiology and Biostatistics, Faculty of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran.
Iranian journal of nursing and midwifery research
|February 9, 2024
概括
细菌感染显著增加孕妇的风险,导致不良妊娠结果,如早产,流产和死产. 早期诊断和干预对于预防严重并发症至关重要.
科学领域:
- 产科和妇科 产科和妇科
- 传染性疾病 传染性疾病
- 围产期健康 围产期健康
背景情况:
- 细菌感染对全球的健康构成严重风险,尤其对孕妇来说.
- 这些感染与严重的妊娠并发症有关,包括流产,早产,死产和宫外妊娠.
研究的目的:
- 系统地审查和元分析细菌感染和不良妊娠结果之间的关系.
- 量化怀孕期间与细菌感染相关的风险.
主要方法:
- 在PubMed,Scopus,Web of Science和Embase数据库 (2000年1月 - 2018年12月) 中进行了系统的文献搜索.
- 选择了相关的研究,并使用纽卡斯尔-太华尺度 (NOS) 对其质量进行了评估.
- 对病例控制研究进行了元分析,以确定各种妊娠结果的几率比率 (OR) 和风险比率 (RR).
主要成果:
- 分析显示,细菌感染显著增加了不良妊娠结果的几率.
- 对于早产婴儿 (OR: 1.50),早产 (OR: 1.54),堕胎 (OR: 1.16),死产 (OR: 1.29) 和宫外妊娠 (OR: 1.12) 观察到特定的增加几率.
- 由于阴道感染而导致的早产的风险比为1.57,而堕胎的风险比为2.02.
结论:
- 孕妇的细菌感染与早产,堕胎,死产和宫外妊娠的风险增加密切相关.
- 医疗保健提供者应优先考虑在怀孕前和怀孕期间诊断细菌感染.
- 积极管理这些感染是减轻妊娠不良后果的关键.
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