骨转移发生在切除明显良性偏瘤52年后:一个病例报告
Run Yu1, Martin S Auerbach2, Nathan S Honda3
1Division of Endocrinology, UCLA David Geffen School of Medicine, Los Angeles, CA, USA.
SAGE open medical case reports
|February 9, 2024
概括
这项研究报告了一种罕见的帕拉结瘤转移到骨的病例,在初始诊断后52年. 长期监测对于帕拉结瘤患者来说至关重要,以检测延迟转移.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 手术病理学手术病理学
背景情况:
- 帕拉格林瘤是具有恶性潜力的神经内分泌瘤.
- 超慢性转移通常发生在最初诊断的几年内.
研究的目的:
- 报告帕拉结瘤诊断和转移之间的异常长时间间隔.
- 强调长期患者监测的重要性.
主要方法:
- 一个71岁的男性患者的病例报告.
- 活检证明的骨转移. 骨转移.
- 诊断成像包括DOTATATE PET.
- 用辐射疗法进行治疗.
主要成果:
- 在最初的 paraganglioma 切除和骨转移之间有52年的间隔.
- 转移呈现为大腿骨的脱落骨折.
- 较高的诺米坦尼林水平证实了活跃的疾病.
- 没有其他转移性病变被DOTATATE PET检测到.
结论:
- 这种病例代表了帕拉结瘤转移的最长报告的延迟之一.
- 长期监测对于帕拉结瘤患者来说至关重要,以确定延迟转移性传播.
- 迅速诊断和治疗转移是非常重要的.
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