后COVID如何与儿童和青少年 (0-20岁) 的其他后病毒状况不同? 一个系统的审查
Chiara Minotti1,2, Carla McKenzie3, Isabelle Dewandel3
1Department of Women's and Children's Health, University of Padua, Italy.
EClinicalMedicine
|February 9, 2024
概括
后冠状病毒疾病 (COVID) 和其他后病毒性疾病在儿童中具有疲劳等症状. 需要进一步的研究来理解后COVID作为一个独特的综合征及其对医疗保健的影响.
科学领域:
- 儿童传染病 儿童传染病
- 后病毒综合征 后病毒综合征
- 公共卫生 公共卫生
背景情况:
- 后病毒综合征,包括后冠状病毒病 (COVID),共享重叠的发病因和症状.
- 与其他后病毒状况相比,了解儿童的后COVID的独特特征至关重要.
研究的目的:
- 系统地审查和描述关于儿童 (0-20岁) 后病毒状况的研究.
- 为了比较儿童的COVID后的特征与其他病毒后疾病.
主要方法:
- 在Embase,MEDLINE,Cochrane图书馆和谷歌学者 (1946-2023) 中进行系统的文献搜索.
- 遵守系统审查和元分析 (PRISMA) 准则的首选报告项目.
- 专注于疾病持续时间,症状类型和慢性症状的发展.
主要成果:
- 分析了35项涉及42,934名儿童的研究,其中28项专注于COVID后.
- 大龄儿童的COVID后症状包括疲劳,神经,心肺,肌肉骨,精神健康和胃肠道问题,持续长达18个月.
- 慢性症状影响36.8%的患者;EBV后表现出类似的疲劳,而RSV/Rhinovirus后在较小的儿童中涉及复发性喘息.
结论:
- 后病毒性疲劳是后COVID和后埃普斯坦-巴尔病毒 (EBV) 条件的常见特征.
- 后COVID需要进一步了解后病毒综合征中的独特实体.
- 标准化定义和结果措施对于评估各种病毒感染的负担和制定管理计划至关重要.
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