晶体镜查 (包括结肠镜) 对结肠直肠癌的影响:基于随机对照试验的元分析
Dongying Wang1, Qian Xu2, Senjie Dai3
1The First Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
内镜查,包括西格莫视镜和结肠镜,显著降低结肠直肠癌 (CRC) 的发病率和死亡率. 这一元分析证实了它在不同癌症部位和性别的有效性.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 预防医学 预防医学
背景情况:
- 结肠直肠癌 (CRC) 仍然是一个重大的全球健康问题.
- 内镜查方法对于早期检测和预防至关重要.
- 调查西格莫显微镜和结肠镜在减少CRC的疗效至关重要.
研究的目的:
- 评估内镜查在减少结直肠癌发病率和死亡率方面的有效性.
- 综合来自随机对照试验 (RCT) 的证据,以分析西格米多镜和结肠镜查结果.
主要方法:
- 进行了系统的文献搜索,直到2023年1月,重点是西格莫视镜和结肠镜查研究.
- 2017年至2022年间发表的五项随机对照试验 (RCT) 被纳入了元分析.
- CRC发病率和死亡率是评估的主要结果.
主要成果:
- 内镜查显著降低了CRC发病率 (RR:0.78) 和死亡率 (RR:0.75).
- 在远端 (发病率:RR:0.66;死亡率:RR:0.62) 和近端CRC (发病率:RR:0.94;死亡率:RR:0.89) 均观察到减少.
- 查证明有效地减少男性和女性的CRC发病率和死亡率.
结论:
- 囊括结肠镜检查的西格莫视镜查是减少结肠直肠癌发病率和死亡率的有效策略.
- 这些发现支持将内镜查纳入用于预防CRC的公共卫生战略.
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