由西-NHC合物联体支持的铁复合物:合成和用于二次化的化
Takashi Komuro1, Kohei Hayasaka1, Kasumi Takahashi1
1Department of Chemistry, Graduate School of Science, Tohoku University, Sendai 980-8578, Japan. takashi.komuro.c5@tohoku.ac.jp.
新的铁复合物催化了用皮纳科尔波兰 (HBpin) 形成N,N-bis () 胺的烯的双化. 这种高效的催化过程在温和条件下实现了高产量,同时催化剂负载较低.
科学领域:
- 有机金属化学 有机金属化学
- 催化剂是一种催化剂.
- 合成化学 合成化学
背景情况:
- 为有机转化开发高效的催化系统至关重要.
- 酸的化为含有有价值的含化合物提供了一条途径.
- 铁复合物越来越多地被探索为贵金属催化剂的可持续替代品.
研究的目的:
- 用于合成新型铁复合物与西-N-异环碳素 (NHC) 双联体.
- 为了研究这些铁复合物的催化活性,在二次化中.
- 探索催化反应的机制,并将活性与鲁同类进行比较.
主要方法:
- 铁复合物的合成,通过Fe3(CO) 12与N-(hydrosilyl) methyl imidazolium盐和基进行反应.
- 在紫外线照射和温和加热下,使用皮纳科尔波兰 (HBpin) 催化双化各种亚烯.
- 使用核磁共振 (NMR) 光谱学的产品的表征.
- 固体测量反应以确定潜在的中间体并阐明催化机制.
主要成果:
- 合成了新型的铁复合物,其中包括西-NHC双联体.
- 获得了高产量 (85% - 95%) 的催化双化,从芳和酸烯酸到N,N-bis () 胺.
- 证明了高的催化效率与低铁复合负荷 (0.5mol%).
- 观察到类似的复合物的活性较低.
- 识别了Fe(0) -N-silylimine复合物作为催化循环中的潜在休眠物种.
结论:
- 新型铁--NHC复合物是二烯双化工的高效催化剂.
- 催化系统在温和条件下 (紫外线照射,60°C) 在低催化剂负载下有效运行.
- 提出了一种涉及Fe(0) -N-silylimine中间体的催化机制,为反应途径提供了洞察力.
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