邻近参与自组合多孔连接的辅助建造和增强客户绑定
Srabani S Mishra1, Shobhana Krishnaswamy1, Dillip Kumar Chand1
1IoE Center of Molecular Architecture, Department of Chemistry, Indian Institute of Technology Madras, Chennai 600036, India.
Journal of the American Chemical Society
|February 9, 2024
概括
合成了新的细胞 (Pd2L4,Pd3L4,Pd4L4). 这些子选择性地结合了像pyrazine-N,N'-dioxide (PZDO) 和化物这样的客分子,结合亲和力随着更多的连接子而增加.
科学领域:
- 超分子化学
- 协调化学
- 材料科学
背景情况:
- 金属有机 (MOC) 越来越多地被研究为宿主-客人化学.
- (II) 复合体为子结构提供了多功能协调几何体.
- 设计器连接物对于控制MOC的大小和功能至关重要.
研究的目的:
- 合成和描述基于的新型单,双和三腔.
- 调查这些子的客结合特性,特别是二氧化 (PZDO) 和化.
- 探索结合系统中的共生形成和增强的结合亲缘关系.
主要方法:
- 酸的复合与各种设计双-,三-和四单联体 (L1-L4).
- 热力学控制 (温度) 和客人诱导 (PZDO) 在子平衡中的变化.
- 离散和连接的结构特征.
- 使用结晶学和结合性研究对客体结合相互作用的分析.
主要成果:
- 成功合成Pd2L4,Pd3L4和Pd4L4,具有单,双和三次腔.
- 发现Pd2L4通过多种非共价相互作用结合PZDO.
- 组合Pd3L4和Pd4L4,包括不同尺寸的Pd2L4单元.
- 在较大的腔体中观察到PZDO的选择性结合,在较小的腔体中观察到阴离子 (NO3-, F-, Cl-, Br-).
- 结合系统中的相邻数量增加了PZDO的结合亲和力.
结论:
- 这项研究证明了多种结构的简单合成.
- 结合的子表现出共生形成,邻近的子相互影响.
- 邻近的子数量显著提高了客人结合的亲和力.
- 这些发现为设计具有可调节性质的复杂主机-客机系统开辟了道路.
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