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对与癌症相关的KIT突变D816V和V560G的药物-蛋白组分析

Heather C Murray1, Kasey Miller1, Matthew D Dun1

  • 1School of Biomedical Sciences and Pharmacy, College of Health, Medicine and Wellbeing, and Precision Medicine Program, Hunter Medical Research Institute, University of Newcastle, Callaghan, New South Wales, Australia.

Proteomics
|February 9, 2024
PubMed
概括

突变的KIT信号驱动癌症. 对D816V和V560G-KIT突变体的蛋白质组分析揭示了蛋白质酶,生长信号和氧化酸化的增加,这表明白血病和GIST等癌症的新治疗点.

关键词:
在 CD117 中,CD117 是 CD117 的第一个版本.癌症 癌症 癌症 癌症 癌症这种白血病是白血病.素蛋白质组学 素蛋白质组学 素蛋白质组学蛋白质组学 蛋白质组学

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