系统性审查 检查药物治疗中的行为变化技术 坚持干预研究 在2型糖尿病患者中进行研究
Vivien Teo1,2, John Weinman1, Kai Zhen Yap2
1Institute of Pharmaceutical Sciences, King's College London (KCL), London, UK.
概括
这项研究确定了成功治疗2型糖尿病患者的关键行为改变技术 (BCT) 和特征. 未来的干预措施应该清楚地描述背景,理论和定制以获得更好的结果.
科学领域:
- 药理学和行为科学 药理学和行为科学
- 临床药房实践 临床药房实践
- 糖尿病管理研究研究 糖尿病管理研究
背景情况:
- 以前的系统性审查显示,对于2型糖尿病 (PwT2D) 患者来说,没有一致的药物坚持干预措施.
- 对干预细节的报告不足,阻碍了药物坚持策略的复制和评估.
- 识别有效的行为改变技术 (BCT) 对于改善PwT2D的坚持至关重要.
研究的目的:
- 确定PwT2D的特定BCT和成功药物坚持干预措施的特征.
- 为开发未来更有效的遵守干预提供基于证据的指导.
- 为应对药物坚持性研究中不一致报告的挑战.
主要方法:
- 在七个主要科学数据库 (Medline,Embase,CINAHL,PsycINFO,Cochrane,Web of Science,Scopus) 进行系统搜索.
- 包括随机对照试验 (RCT) 与BCT可编码的干预措施,以针对PwT2D (年龄18岁以上) 的抗糖尿病药物坚持.
- 专注于测量药物坚持作为主要或次要结果的研究.
主要成果:
- 55项研究符合纳入标准.
- 成功的干预措施往往专门针对遵守,涉及药剂师,并使用BCT,如"可信来源" (9.1),"如何执行行为指令" (4.1),"社会支持 (实用) " (3.2),"行动计划" (1.4),和"关于健康后果的信息" (5.1).
- 很少有干预措施充分描述了上下文,使用了理论,评估了干预后的坚持,或者是针对特定患者障碍量身定制的.
结论:
- 在PwT2D中,特定的BCT和干预特征与成功的药物坚持有关.
- 未来的干预开发需要对背景,理论基础,忠实性和定制策略的明确报告.
- 本次审查为为糖尿病管理创建更有效和可重复的药物坚持干预措施提供了基础.
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